We had thought of that as well, but it turns out AFAIK we have it right.
Another team at our school, 4221B, has their Mecanum wheels mounted the same way we have ours. We downloaded their program to our Cortex, and it worked. They never had any similar issues, nor has anyone at our school.
If you mean that fwd/reverse works but the robot turns left when it should turn right etc.
Then swap motors for left and right sides in the holo block. Presently you have 1&9 on the left and 2&10 on the right. All motors are inverted in the code you posted (which is unusual, normally only one side would be inverted). Check that this block is configured correctly and you didn’t swap left and right and/or get the motor inversion wrong, ie. should only the right side be inverted?